Quantification of intracerebral steal in patients with arteriovenous malformation

Journal Article · Fri Aug 01 04:00:00 EDT 1986 · Arch. Neurol.; (United States)

DOI:https://doi.org/10.1001/archneur.1986.00520080027015· OSTI ID:5125157

Homan, R W; Devous, Sr, M D; Stokely, E M; Bonte, F J

Eleven patients with angiographically and/or pathologically proved arteriovenous malformations (AVMs) were studied using dynamic, single-photon-emission computed tomography (DSPECT). Quantification of regional cerebral blood flow in structurally normal areas remote from the AVM disclosed areas of decreased flow compared with normal controls in eight of 11 patients examined. Areas of hypoperfusion correlated with altered function as manifested by epileptogenic foci and impaired cognitive function. Dynamic, single-photon-emission computed tomography provides a noninvasive technique to monitor quantitatively hemodynamic changes associated with AVMs. Our findings suggest that such changes are present in the majority of patients with AVMs and that they may be clinically significant. The potential application of regional cerebral blood flow imaging by DSPECT in the management of patients with AVMs is discussed.

• OSTI ID: 5125157
• Journal Information: Arch. Neurol.; (United States), Journal Name: Arch. Neurol.; (United States) Journal Issue: 8 Vol. 8; ISSN ARNEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD FLOW
BLOOD VESSELS
BODY
BRAIN
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
EPILEPSY
MALFORMATIONS
NERVOUS SYSTEM
NERVOUS SYSTEM DISEASES
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
TOMOGRAPHY