Evidence of redistribution of cerebral blood flow during treatment for an intracranial arteriovenous malformation

Journal Article · Sun Oct 01 04:00:00 EDT 1989 · Neurosurgery; (USA)

DOI:https://doi.org/10.1097/00006123-198910000-00014· OSTI ID:5261971

Batjer, H H; Purdy, P D; Giller, C A; Samson, D S ^[1]

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1. Univ. of Texas Southwestern Medical Center, Dallas (USA)

The presence of an intracranial arteriovenous malformation has a dramatic impact on local circulatory dynamics. Treatment of some arteriovenous malformations can result in disastrous hyperemic states caused by redistribution of previously shunted blood. This report describes serial hemodynamic measurements of both cerebral blood flow and flow velocity in 3 patients during treatment for arteriovenous malformations. Measurements of cerebral blood flow were made by computed tomographic scan employing the stable xenon inhalation technique; flow velocity, including autoregulatory characteristics, was measured by transcranial Doppler ultrasonogram. Substantial hyperemia developed in one patient (Case 1) after resection and in another (Case 3) after embolization. Embolization resulted in restoration of normal regional cerebral blood flow in a patient who demonstrated hypoperfusion before treatment (Case 2). In Patient 1, postoperative hyperemia was associated with persistently elevated flow velocities, and may have been accompanied by hemispheric neurological deficits. Sequential hemodynamic measurements may predict patients at risk of perioperative complications, and may become useful clinical guidelines for the extent and timing of embolization and for the timing of surgery after intracranial hemorrhage or preoperative embolization procedures.

• OSTI ID: 5261971
• Journal Information: Neurosurgery; (USA), Journal Name: Neurosurgery; (USA) Vol. 25:4; ISSN 0148-396X; ISSN NRSRD
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD FLOW
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CEREBRAL CORTEX
CEREBRUM
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
ISOTOPES
NERVOUS SYSTEM
ORGANS
PATIENTS
TOMOGRAPHY
ULTRASONOGRAPHY
VASCULAR DISEASES
XENON ISOTOPES