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Cerebral hemodynamics in arteriovenous malformations: evaluation by single-photon emission CT

Journal Article · · AJNR, Am. J. Neuroradiol.; (United States)
OSTI ID:6522307
Cerebral hemodynamics in six patients with supratentorial arteriovenous malformations (AVMs) were studied by using single-photon emission CT with three types of radioactive isotopes: N-isopropyl-p-(/sup 123/I) iodoamphetamine, /sup 81m/Kr, and /sup 99m/Tc-RBC in order to determine the local cerebral blood flow and blood volume associated with these malformations. The AVMs were shown to have high flow while other areas of the brain, including the contralateral hemisphere, had variable areas of diminished perfusion. There was increased blood volume in the regions of AVMs, and poor but evenly distributed blood volume in the other regions. CO/sub 2/ reactivity during hypocapnia was preserved throughout the brain except for the region of the AVMs. In large AVMs, the ischemic state surrounding the nidus was considered to be caused mainly by the cerebral steal phenomenon.
Research Organization:
National Cardiovascular Center, Osaka, Japan
OSTI ID:
6522307
Journal Information:
AJNR, Am. J. Neuroradiol.; (United States), Journal Name: AJNR, Am. J. Neuroradiol.; (United States) Vol. 2; ISSN AAJND
Country of Publication:
United States
Language:
English

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