Improved computer-assisted nuclear imaging in renovascular hypertension

Journal Article · Sun Dec 01 04:00:00 EST 1985 · J. Clin. Hypertens.; (United States)

OSTI ID:5123747

Gross, M L; Nally, J V; Windham, J P; Clarke, H S; Riccobono, X J; Potvin, W J

Computer-assisted dynamic renal studies using both the 90 second /sup 99m/Tc-DTPA and the conventional 30 minute 131I-Hippuran methods were performed in nine patients with angiographically proven renal artery stenosis. Time activity curves for both studies were derived from regions of interest selected from the computer-acquired dynamic images. The following parameters were used to assess renal blood flow: differential maximum activity, minimum/maximum activity ratio, and peak width. The computer-assisted DTPA study accurately predicted (9/9) the stenotic side documented angiographically, whereas the conventional Hippuran scan was clearly predictive in only 57% (5/9). The best discriminatory factors for the 90 second /sup 99m/Tc-DTPA scan, when compared to a normal template synthesized from curves obtained from normal subjects (20), were differential maximum activity and peak width. In conclusion, the computer-assisted 90 second /sup 99m/Tc-DTPA renal blood flow scan was superior to the conventional 30 minute 131I-Hippuran scan in demonstrating unilateral renovascular disease. The DTPA study was highly predictive of the angiographic findings, and this noninvasive study may prove useful in the diagnosis and serial evaluation following surgery or angioplasty in patients having renal artery stenosis.

• OSTI ID: 5123747
• Journal Information: J. Clin. Hypertens.; (United States), Journal Name: J. Clin. Hypertens.; (United States) Vol. 4; ISSN JCHYE
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BLOOD FLOW
BLOOD VESSELS
BODY
CARBOXYLIC ACIDS
CARDIOVASCULAR SYSTEM
CHELATING AGENTS
COMPARATIVE EVALUATIONS
COMPUTERS
CONTRAST MEDIA
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DTPA
HIPPURAN
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KIDNEYS
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RADIOPROTECTIVE SUBSTANCES
TECHNETIUM 99
TECHNETIUM ISOTOPES
VASCULAR DISEASES
YEARS LIVING RADIOISOTOPES