Measures of de novo synthesis of milk components from propionate in lactating goats

Journal Article · Fri Feb 01 04:00:00 EST 1985 · J. Dairy Sci.; (United States)

DOI:https://doi.org/10.3168/jds.S0022-0302(85)80827-4· OSTI ID:5095230

Emmanuel, B; Kennelly, J J

Possible direct contributions of propionate to de novo synthesis of milk components by the mammary gland of lactating goats fed a concentrate-roughage diet have been studied in vivo by primed constant infusion of (1-carbon-14)propionate into the right mammary artery. Specific radioactivities of milk galactose, fatty acids, and protein were higher in the infused than in the uninfused half of the mammary gland, suggesting de novo synthesis of these compounds in the udder. Specific radioactivities of milk glucose in both udder halves were identical, ruling out any possibility of mammary gland-derived glucose from propionate of blood plasma under the experimental conditions. Of milk galactose, .8% was derived from propionate of blood plasma, and of milk glucose, 98% was derived from glucose of blood plasma. After intraruminal infusion of unlabeled propionic acid at 11 g/h, concentration of propionate in blood plasma was doubled, its contribution to milk galactose was increased to 1.5%, and proportions of milk odd-numbered fatty acids were increased. Propionate was incorporated largely into milk odd-numbered fatty acids. The authors conclude that small amounts of propionate can be incorporated into principal components of milk in the mammary gland of lactating goats.

• Research Organization: Univ. of Alberta, Edmonton, Canada
• OSTI ID: 5095230
• Journal Information: J. Dairy Sci.; (United States), Journal Name: J. Dairy Sci.; (United States) Vol. 2; ISSN JDSCA
• Country of Publication: United States
• Language: English

Related Subjects

551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ALDEHYDES
ANIMALS
BIOLOGICAL MATERIALS
BIOSYNTHESIS
BODY
BODY FLUIDS
CARBOHYDRATES
CARBON 14 COMPOUNDS
CARBOXYLIC ACIDS
DOMESTIC ANIMALS
FOOD
GALACTOSE
GLANDS
GLUCOSE
GOATS
HEXOSES
LABELLED COMPOUNDS
LACTATION
MAMMALS
MAMMARY GLANDS
MATERIALS
METABOLISM
MILK
MONOCARBOXYLIC ACIDS
MONOSACCHARIDES
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PREGNANCY
PROPIONIC ACID
RUMINANTS
SACCHARIDES
SYNTHESIS
VERTEBRATES