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Radiation therapy of early carcinoma of the breast without mastectomy. [Linear acceleraor and iridium implants]

Journal Article · · Cancer; (United States)
OSTI ID:5072281
; ;
The results of the treatment of 176 patients with early breast cancer, using radiation therapy without mastectomy are reported. The likelihood of local recurrence was 5% for Stage I patients and 7% for Stage II patients. Local control was significantly greater in those patients receiving an iridium implant. The cumulative survival probability at five years is 96% for Stage I and 68% for Stage II. Gross tumor resection with careful reapproximation of the breast tissue and well-placed incisions facilitates the radiation therapy. Homogeneous external beam radiation to the breast and draining lymph nodes (4500 to 5000 rads) and supplemental local radiation to the sites of the primary lesion (in this series using interstitial implantation) are recommended. The frequency of normal tissue complications was low.
Research Organization:
Harvard Medical School, Boston, MA
OSTI ID:
5072281
Journal Information:
Cancer; (United States), Journal Name: Cancer; (United States) Vol. 46:4; ISSN CANCA
Country of Publication:
United States
Language:
English

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Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
560161 -- Radionuclide Effects
Kinetics
& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACCELERATORS
ARMS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CARCINOMAS
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
DELAYED RADIATION EFFECTS
DISEASES
EDEMA
ELEMENTS
ENERGY RANGE
FIBROSIS
GLANDS
HEART
IMPLANTS
IRIDIUM
LIMBS
LINEAR ACCELERATORS
LUNGS
MAMMARY GLANDS
MEDICINE
MEMBRANES
METALS
MEV RANGE
MEV RANGE 01-10
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
PERICARDIUM
PLATINUM METALS
PNEUMONITIS
RADIATION EFFECTS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
REFRACTORY METALS
RESPIRATORY SYSTEM
SEROUS MEMBRANES
SIDE EFFECTS
SURVIVAL TIME
SYMPTOMS
THERAPY
TRANSITION ELEMENTS