Biopsy and definitive radiation therapy in stages I and II carcinoma of the female breast
Journal Article
·
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
One hundred-twenty patients with Stages I and II carcinoma of the female breast were biopsied followed by definitive radiation therapy without mastectomy. The breast received 4500-5000 cGy (rad) using a 6 MV linear accelerator followed by a supplement to the area of the primary tumor of 2000 cGy (rad) using electrons in 99 patients (83%) and interstitial implanation in 21 patients (17%). Local recurrence was not recorded in the 43 patients with Stage I disease, while three of 77 patients (4%) with Stage II disease suffered a local recurrence. The actuarial five-year relapse-free survival was 91% and 60% in Stages I and II respectively. Cosmetic results were considered excellent by both physician and patient in the majority of cases. Axillary dissection was the recommended method of staging the axilla but was noted to be more morbid than axillary sampling. Electrons may be as effective as interstitial implanation as a means of supplementation following external beam therapy if specific guidelines are followed.
- Research Organization:
- Palo Alto Medical Foundation, CA
- OSTI ID:
- 5020684
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 9:1; ISSN IOBPD
- Country of Publication:
- United States
- Language:
- English
Similar Records
Results of conservative surgery and radiation therapy for breast cancer
Radiation therapy of early carcinoma of the breast without mastectomy. [Linear acceleraor and iridium implants]
Clinical investigation: Regional nodal failure patterns in breast cancer patients treated with mastectomy without radiotherapy
Journal Article
·
Mon Oct 01 00:00:00 EDT 1990
· Surgical Clinics of North America; (USA)
·
OSTI ID:6069384
Radiation therapy of early carcinoma of the breast without mastectomy. [Linear acceleraor and iridium implants]
Journal Article
·
Fri Aug 15 00:00:00 EDT 1980
· Cancer; (United States)
·
OSTI ID:5072281
Clinical investigation: Regional nodal failure patterns in breast cancer patients treated with mastectomy without radiotherapy
Journal Article
·
Wed Nov 30 23:00:00 EST 2005
· International Journal of Radiation Oncology, Biology and Physics
·
OSTI ID:20788247
Related Subjects
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCELERATORS
ANIMALS
BIOPSY
BODY
CARCINOMAS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTROMAGNETIC RADIATION
ELECTRONS
ELEMENTARY PARTICLES
FEMALES
FERMIONS
GLANDS
HARD X RADIATION
IMPLANTS
IONIZING RADIATIONS
LEPTONS
LINEAR ACCELERATORS
LYMPH NODES
LYMPHATIC SYSTEM
MAMMALS
MAMMARY GLANDS
MAN
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PRIMATES
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIATIONS
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURVIVAL TIME
THERAPY
VERTEBRATES
WOMEN
X RADIATION
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCELERATORS
ANIMALS
BIOPSY
BODY
CARCINOMAS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTROMAGNETIC RADIATION
ELECTRONS
ELEMENTARY PARTICLES
FEMALES
FERMIONS
GLANDS
HARD X RADIATION
IMPLANTS
IONIZING RADIATIONS
LEPTONS
LINEAR ACCELERATORS
LYMPH NODES
LYMPHATIC SYSTEM
MAMMALS
MAMMARY GLANDS
MAN
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PRIMATES
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIATIONS
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURVIVAL TIME
THERAPY
VERTEBRATES
WOMEN
X RADIATION