Raman-based system for DNA sequencing-mapping and other separations
Patent
·
OSTI ID:5017940
DNA sequencing and mapping are performed by using a Raman spectrometer with a surface enhanced Raman scattering (SERS) substrate to enhance the Raman signal. A SERS label is attached to a DNA fragment and then analyzed with the Raman spectrometer to identify the DNA fragment according to characteristics of the Raman spectrum generated. 11 figures.
- DOE Contract Number:
- AC05-84OR21400
- Assignee:
- Martin Marietta Energy Systems, Inc., Oak Ridge, TN (United States)
- Patent Number(s):
- US 5306403; A
- Application Number:
- PPN: US 7-933376
- OSTI ID:
- 5017940
- Resource Relation:
- Patent File Date: 24 Aug 1992
- Country of Publication:
- United States
- Language:
- English
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