Applications of brain blood flow imaging in behavioral neurophysiology: cortical field activation hypothesis

Journal Article · Tue Jan 01 04:00:00 EST 1985 · Res. Publ., Assoc. Res. Nerv. Ment. Dis.; (United States)

OSTI ID:5012815

Roland, P E

The /sup 133/xenon intracarotid method for rCBF measurements has been a very useful method for functional mapping and functional dissection of the cerebral cortex in humans. With this method it has been shown that different types of cortical information treatment activate different cortical areas and furthermore that sensory and motor functions of the cerebral cortex could be dissected into anatomical and informational subcomponents by behavioral manipulations. The brain organizes its own activity. One of the principles of organization was that the brain could recruit in advance cortical fields that were expected to participate in a certain type of information operation. During brain work in awake human beings the cerebral cortex was activated in fields that, projected on the cerebral surface, most often had a size greater than 3 CM/sup 2/. Such activated fields appeared no matter which type of information processing was going on in the brain: during planning and execution of voluntary movements, during preparation for sensory information processing, and during sensory information processing, as well as during cognitive brain work and retrieval of specific memories. Therefore, it was hypothesized that cortical field activation was the physiological manifestation of normal brain work in awake humans.

• Research Organization: Karolinska Hospital, Stockholm, Sweden
• OSTI ID: 5012815
• Journal Information: Res. Publ., Assoc. Res. Nerv. Ment. Dis.; (United States), Journal Name: Res. Publ., Assoc. Res. Nerv. Ment. Dis.; (United States); ISSN RPARA
• Country of Publication: United States
• Language: English

Related Subjects

551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ALDEHYDES
BEHAVIOR
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
CEREBRAL CORTEX
CEREBRUM
DAYS LIVING RADIOISOTOPES
DYNAMIC FUNCTION STUDIES
EVEN-ODD NUCLEI
GLUCOSE
HEXOSES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MONOSACCHARIDES
NERVOUS SYSTEM
NUCLEI
ORGANIC COMPOUNDS
ORGANS
RADIOISOTOPES
SACCHARIDES
SPEECH
XENON 133
XENON ISOTOPES