Distribution of 15- and 137-mu diameter microspheres in the dog lung in the axial plane
Journal Article
·
· Invest. Radiol.; (United States)
Oleic acid infusion, as a model of fat embolism, produces a predominantly peripheral lesion in the dog lung. The lung injury corresponds to the peripheral distribution of labeled oleic acid. The basis for this distribution of oleic acid is not known. Our hypothesis for this nonuniform distribution is that particle diameter plays a role in the subsequent distribution of infused oleic acid and the resulting lung injury. We injected 15-mu microspheres /sup 85/Sr and then 137-mu microspheres (/sup 141/Ce) into the right atria of seven dogs, which were killed and the lungs removed. Analysis of the distribution of the two different diameter microspheres within axial slices from the left caudal lobe of each dog revealed a peripheral distribution of the larger diameter microspheres not seen with the smaller microspheres.
- Research Organization:
- Duke Univ. Medical Center, Durham, NC
- OSTI ID:
- 5003322
- Journal Information:
- Invest. Radiol.; (United States), Journal Name: Invest. Radiol.; (United States) Vol. 8; ISSN INVRA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560172* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
CERIUM 141
CERIUM ISOTOPES
DAYS LIVING RADIOISOTOPES
DISTRIBUTION
DOGS
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LUNGS
MAMMALS
MICROSPHERES
NUCLEI
ORGANS
PARTICLE SIZE
RADIOISOTOPES
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
RESPIRATORY SYSTEM
SIZE
STRONTIUM 85
STRONTIUM ISOTOPES
TISSUE DISTRIBUTION
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
CERIUM 141
CERIUM ISOTOPES
DAYS LIVING RADIOISOTOPES
DISTRIBUTION
DOGS
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LUNGS
MAMMALS
MICROSPHERES
NUCLEI
ORGANS
PARTICLE SIZE
RADIOISOTOPES
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
RESPIRATORY SYSTEM
SIZE
STRONTIUM 85
STRONTIUM ISOTOPES
TISSUE DISTRIBUTION
VERTEBRATES