POSTOPERATIVE TREATMENT OF THYROID CANCER WITH RADIOACTIVE IODINE

Conference · Sat Jun 15 04:00:00 EDT 1963

OSTI ID:4876193

Blahd, William H.; Koplowitz, Jerry M.

Experiences in the postoperative treatment of thyroid cancer with radioactive iodine since 1949 are reviewed. Forty-five patients received therapeutic amounts of I/sup 131/ and were followed for more than one year. Cancer metastases were localized by means of the mechanical scintiscanner after patients had received large tracer doses of I/sup 131/ preceded by injections of thyrotropic hormone. A consistent therapeutic regimen was followed involving four basic modalities of therapy: surgical thyroidectomy, thyrotropic hormone stimulation, cancerocidal doses of I/sup 131/ and thyroid extract administration. Twenty-nine patients in the series had proved metastatic lesions; 11 died, 18 are living, and 41% have lived 5 or more years. All patients who were free of metastases after initial thyroid surgery are alive. No complications from I/sup 131/ therapy were observed. This is attributed to the conservative dosage regimen employed. The results of the use of I/sup 131/ in the postoperative treatment of thyroid cancer in other reported series are also reviewed. (P.C.H.)

• Research Organization: Veterans Administration Center, Los Angeles, CA (United States); Univ. of California, Los Angeles, CA (United States). School of Medicine
• Sponsoring Organization: Sponsor not identified
• NSA Number: NSA-17-035594
• OSTI ID: 4876193
• Report Number(s): CONF-164-4
• Country of Publication: United States
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
CANCER
HORMONES
IODINE 131
MAN
METASTASES
RADIATION DETECTORS
RADIOTHERAPY
SCINTILLATION COUNTERS
SURGERY
SURVIVAL TIME
THYROID
TISSUE EXTRACTS
TRACER TECHNIQUES
TSH