HAEMATOLOGICAL AND HISTOLOGICAL STUDIES IN THE OFFSPRING OF ALBINO RATS AFTER Sr*SUP 90/ ADMINISTRATION. I. HAEMATOLOGICAL AND HISTOLOGICAL OBSERVATIONS IN THE ALBINO RATS AFTER Sr*SUP 90/ ADMINISTRATION

Journal Article · Thu Jan 01 04:00:00 EST 1959 · Naika Hokan (Japan)

OSTI ID:4839271

Nishimura, K

No appreciable hematological changes were seen following a single injection of Sr/sup 90/ in a dose of 0.2 mu c/g of body weight. A single dose of 0.5-1.5 mu c of Sr/sup 90/ or successive injections of 0.2 mu c for 5 weeks resulted in a marked decrease of neutrophilic leukocytes, as well as the delayed decrease of the lymphocytes and thrombocytes; the erythrocytes were influenced the least. The deposition of Sr/sup 90/ 12 months later was shown to be mostly in the bone and a little in the other viscera. Osteogenic sarcoma developed in the epiphysis of the femur and the humerus of 3 rats out of 12. The animals are still surviving more than 6 months after the injection of Sr/sup 90/. (Abstr. Japsn Med., 1: No. 10, 1961)

• Research Organization: Kyoto Univ.
• NSA Number: NSA-15-027441
• OSTI ID: 4839271
• Journal Information: Naika Hokan (Japan), Journal Name: Naika Hokan (Japan) Vol. Vol: 6; ISSN NAHOA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD
BONES
ERYTHROCYTES
LEUCOCYTES
QUANTITY RATIO
RATS
STRONTIUM 90
TISSUES
TUMORS