Toxicity of Tritiated Thymidine to Bone Marrow Transplants
Damage in the precursors of blood cells due to incorporation of tritiated thymidine was evaluated in vivo. The parameter measured was the speed of recovery of peripheral blood cells after isologous marrow transplantation in irradiated mice. Donor animals received a total of either 20 or 40 mu C of H3-thymidine per gm of body weight. A delay in recovery was demonstrable only with small inocula, even after the very large doses of triated thymidine were administered.
- Research Organization:
- National Cancer Inst.; National Inst. of Arthritis and Metabolic Diseases; National Heart Inst., Bethesda, Md.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-16-017507
- OSTI ID:
- 4835602
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Journal Issue: 2 Vol. 16; ISSN 0033-7587
- Publisher:
- Radiation Research Society
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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