STUDIES OF IRON METABOLISM IN THE RAT FOLLOWING X-IRRADIATION (EXPERIMENTAL STUDIES WITH RADIOACTIVE IRON). I. THE KINETICS OF IRON METABOLISM AFTER SINGLE EXPOSURE

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Nippon Igaku Hoshasen Gakkai Zasshi (Japan)

OSTI ID:4828304

Maeda, M; Nakanishi, K

Iron turn-over rates in the plasma and erythrocytes of the rat were studied at 24 bours after whole-body irradiation with doses of I00 and 200 r using Fe/sup 59/. The iron clearance time of the plasma was prolonged after irradiation, but the plasma turn-over rate/kg body weight/day increased in irradiated rats, due to the elevated plasma iron level. The relative erythrocyte uptake of Fe/sup 59/ was so severely depressed by x irradiation that the erythrocyte iron turn-over rate decreased proportionally as the x-ray doses increased. The Fe/sup 59/ content in the liver 6 days after injection increased in irradiated rats. An exponential relation was generally found between irradiation doses and the changes produced. (Abstr. Japan Med., 1: No. 13, I96l)

• Research Organization: Kyoto Prefectural Univ.
• NSA Number: NSA-16-004091
• OSTI ID: 4828304
• Journal Information: Nippon Igaku Hoshasen Gakkai Zasshi (Japan), Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi (Japan) Vol. Vol: 20; ISSN NHGZA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD PLASMA
ERYTHROCYTES
IRON
IRON 59
LIVER
METABOLISM
RADIATION DOSES
RADIATION EFFECTS
RATS
TRACER TECHNIQUES
X RADIATION