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Effect of Total Body Irradiation on Iron Metabolism in Human Bone Marrow

Journal Article · · British Journal of Radiology
Results of hematological and iron metabolism investigations on 17 patients who received total body x irradiation are presented. In vivo iron tracer studies indicate that 25 to 50 r total body irradiation to man 24 hours before an injection of Fe⁵⁹ does not delay the appearance of the radioactive iron in the peripheral erythrocytes. One hundred rontgens total body irradiation to man does not delay the appearance of Fe⁵⁹ in the peripheral erythrocytes if the tracer is given two hours after the irradiation, but if the tracer is given 24 to 72 hours after irradiation there is a definite delay in the appearance of the Fe/sup 59/ in the erythrocytes. The probable mechanisms for producing the delay in the appearance of the Fe/sup 59/ in the peripheral erythrocytes are discussed. (auth)
Research Organization:
Churchill Hospital, Oxford
Sponsoring Organization:
USDOE
NSA Number:
NSA-12-000021
OSTI ID:
4842654
Journal Information:
British Journal of Radiology, Journal Name: British Journal of Radiology Journal Issue: 358 Vol. 30; ISSN 0007-1285
Country of Publication:
Country unknown/Code not available
Language:
English

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