STUDY ON THE BIOLOGICAL EFFECT OF X-RAY IRRADIATION ON THE HEART. I. THE EFFECT ON THE CARDIAC METABOLISM

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Nippon Junkanki Gakushi (Japan) Changed to Jpn. Circ. J.

OSTI ID:4828202

Kurata, N

Coronary sinus catheterization was performed in 13 dogs. Following an irradiation of 4,000 r to the heart, the A-V difference of glucose in the coronary sinus was decreased; pyruvic and lactic acids and creatine were temporarily increased. Following irradiation of 1,000 to 4,000 r to the hearts of 28 rabbits, the glycogen in the heart muscle decreased, while the glucose, pyruvic and lactic acids, creatine and creatinine contents temporarily increased. In irradiated dogs and rabbits, the porphyrin affinity of the heart muscle was diminished. In 6 toads, no change was found in the lactic dehydrogenase activity even after 6925 r irradiation to the heart. The disturbance of glucose metabolism in the irradiated heart muscle appears to be not in the anaerobic processes but in the aerobic phase, especially in the electron transport system in the mitochondria. (auth)

• Research Organization: Mie Prefectural Univ., Tsu, Japan
• NSA Number: NSA-16-004096
• OSTI ID: 4828202
• Journal Information: Nippon Junkanki Gakushi (Japan) Changed to Jpn. Circ. J., Journal Name: Nippon Junkanki Gakushi (Japan) Changed to Jpn. Circ. J. Vol. Vol: 25; ISSN NJUGA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AMPHIBIANS
ANIMALS
BIOLOGY AND MEDICINE
CARBOHYDRATES
DOGS
ELECTRONS
GLUCOSE
GLYCOGEN
HEART
KETONES
LACTIC ACID
METABOLISM
MITOCHONDRIA
ORGANIC ACIDS
POLYSACCHARIDES
PYRUVIC ACID
QUANTITY RATIO
RABBITS
RADIATION DOSES
RADIATION EFFECTS
SUGARS
TOADS
TRANSPORT
X RADIATION