Effect of mercuric chloride on some biochemical and physiological parameters of the freshwater murrel, Channa punctatus
The freshwater murrel, Channa punctatus, was exposed to a sublethal concentration of mercuric chloride (3 ..mu..g/liter) for 120 days and the following effects were examined: changes in the levels of glucose and lactic acid in blood and of glycogen and lactic acid in liver and muscles; rate of absorption of glucose from the intestine; and changes in the activities of glucose-6-phosphatase (G-6-Pase), hexokinase, lactate dehydrogenase (LDH), pyruvate dehydrogenase (PDH), succinate dehydrogenase (SDH), malate dehydrogenase (MDH), glutamate dehydrogenase (GDH), L-amino acid oxidase (AO), and xanthine oxidase (XO) in brain, gills, intestine, kidney, liver, and muscles. Mercury-treated fish were hypoglycemic and hypolactemic. The glycogen content of liver and muscles remained unaltered but the muscle lactic acid level decreased significantly. The rate of intestinal absorption of glucose was reduced significantly by exposure to mercury. G-6-Pase activity was decreased in all the tissues. Hexokinase activity also decreased in mercury-exposed fish but it was significant only in intestine, kidney, and liver. The activities of LDH, PDH, SDH, and MDH also were decreased significantly except LDH in brain and MDH in kidney where an insignificant decrease and an insignificant increase, respectively, were recorded. GDH and AO activities were elevated in most of the tissues except GDH in gills, and AO in gills and muscles where a decrease was observed. XO activity in brain, gills, and kidneys was significantly elevated, but no marked alteration was noted in other tissues.
- Research Organization:
- DAV Coll., Muzaffarnagar, India
- OSTI ID:
- 5995359
- Journal Information:
- Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 34:2; ISSN ENVRA
- Country of Publication:
- United States
- Language:
- English
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Chronic effects of mercuric chloride on the activities of some enzymes in certain tissues of the fresh water murrel, Channa punctatus
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ALDEHYDES
ANIMALS
AQUATIC ORGANISMS
BIOCHEMICAL REACTION KINETICS
BIOCHEMISTRY
BODY
BRAIN
CARBOHYDRATES
CARBOXYLIC ACIDS
CENTRAL NERVOUS SYSTEM
CHEMISTRY
CHLORIDES
CHLORINE COMPOUNDS
DATA
DIGESTIVE SYSTEM
ENZYME ACTIVITY
ENZYMES
ESTERASES
EXPERIMENTAL DATA
FISHES
GASTROINTESTINAL TRACT
GILLS
GLANDS
GLUCOSE
GLYCOGEN
HALIDES
HALOGEN COMPOUNDS
HEXOKINASE
HEXOSES
HYDROLASES
HYDROXY ACIDS
INFORMATION
INTESTINAL ABSORPTION
INTESTINES
KIDNEYS
KINETICS
LACTIC ACID
LIVER
MERCURY CHLORIDES
MERCURY COMPOUNDS
MERCURY HALIDES
MONOSACCHARIDES
MUSCLES
NERVOUS SYSTEM
NUMERICAL DATA
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
OXIDOREDUCTASES
PHOSPHATASES
PHOSPHORUS-GROUP TRANSFERASES
PHOSPHOTRANSFERASES
PHYSIOLOGY
POLYSACCHARIDES
REACTION KINETICS
RESPIRATORY SYSTEM
SACCHARIDES
TOXICITY
TRANSFERASES
UPTAKE
VERTEBRATES