CHROMATOGRAPHY AND NUCLEOTIDE SEQUENCES OF DEOXYRIBONUCLEIC ACID SYNTHESIZED IN SALMONELLA TYPHIMURIUM AFTER IRRADIATION WITH ULTRA-VIOLET

Journal Article · Sat Nov 11 04:00:00 EST 1961 · Nature

DOI:https://doi.org/10.1038/192554a0· OSTI ID:4825501

Hudnik-Plevnik, T; Stocken, L A

It is shown that ultraviolet radiation produces a temporary inhibition of desoxyribonucleic acid (DNA) synthesis in the bacteria Salnionella typhimurium. The synthesis is resumed after 30 to 60 minutes and proceeds at a rate similar to the control, but the surviving bacteria are growing only in mass, having lost their ability to form colonies. Thus results are presented of the chromatography and nucleotide sequences for the characterization of DNA from normal and irradiated Sal. typhimurium. The net results of the synthesis show that DNA formed in the irradiated bacteria is less stable and the turnover correspondingly greater, however, the synthesis is roughly the same in the two cases. (N.W.R.)

• Research Organization: Oxford Univ.
• Sponsoring Organization: USDOE
• NSA Number: NSA-16-004065
• OSTI ID: 4825501
• Journal Information: Nature, Journal Name: Nature Vol. Vol: 192
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BACTERIA
BIOCHEMISTRY
BIOLOGY AND MEDICINE
CHROMATOGRAPHY
METABOLISM
NUCLEIC ACIDS
ULTRAVIOLET RADIATION