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MYOCARDIAL BLOOD FLOW DETERMINED WITH KRYPTON 85 IN UNANESTHETIZED DOGS

Journal Article · · American Journal of Physiology (U.S.)
OSTI ID:4822503
Serial, rapid measurements of left ventricular myocardial blood flow in trained, unanesthetized dogs have been made by injecting krypton-85 through chronically implanted coronary artery catheters and counting with an external scintillation detector. Precordial radioactivity declined as a single exponential function during the first 2 min after injection, suggesting a single rate of myocardial blood flow. Simultaneous estimations with Kr/sup 85/ and blood flowmeters in acute experiments established the accuracy and reproducibility of the technique. Myocardial blood flows between 40 and 55 ml/ 1OO g/min were observed repeatedly in three well-trained, unanesthetized dogs in the basal state. (auth)
Research Organization:
Harvard Medical School, Boston
NSA Number:
NSA-16-023362
OSTI ID:
4822503
Journal Information:
American Journal of Physiology (U.S.), Journal Name: American Journal of Physiology (U.S.) Vol. Vol: 203; ISSN AJPHA
Country of Publication:
Country unknown/Code not available
Language:
English

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