LUMINESCENCE STUDIES IN EARLY RADIATION INJURIES OF CELLS (in Russian)
Journal Article
·
· Izvest. Akad. Nauk S.S.S.R., Ser. Biol.
OSTI ID:4820416
Vital and supravital methods of luminescence microscopy render it possible to reveal in hemopoietic organs almost immediately after irradiation marked physico-chemical and structural injuries of the nuclei of individual celIs, the number of such injured cells increasing within a few hours after irradiation. Conventional histological methods cannot reveal such early disturbances. In lymphocytes and lymphoid organs (lymphatic nodes, thymus) early nuclear disorders are of the same character as that previously described in the nuclei of bone marrow cells of irradiated animals. Radiation-injured cells of lymphoid organs are arranged in individual foci, their aggrevation resembIing micronecrotic foci in the bone marrow. Early nuclear lesions of cells in lymphoid organs are caused by direct action of radiation. Screening eliminates this reaction. Stratification of nuclear nucleoprotein into two fractions with a different luminescence apparently reflects the separation of DNA from protein. Early nuclear injuries are revealed also in the epithelium of the small intestine of irradiated animals. Luminescence-microscopic methods both in the visibIe and uItraviolet range of the spectrum are already used with success in radiobiological experiments. They are also very promising for the study of the nature of biological action of radiation. (auth)
- Research Organization:
- Inst. of Radiation and Physico-Chemical Biology, Academy of Sciences, Moscow; and Inst. of Biophysics, Academy of Sciences, Moscow
- NSA Number:
- NSA-16-001534
- OSTI ID:
- 4820416
- Journal Information:
- Izvest. Akad. Nauk S.S.S.R., Ser. Biol., Journal Name: Izvest. Akad. Nauk S.S.S.R., Ser. Biol. Vol. Vol: No. 5
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
Similar Records
MICRONECROTIC FOCI IN THE SPLEEN OF IRRADIATED ANIMALS
ON THE NATURE OF MICRONECROTIC FOCI IN HEMOPOIETIC ORGANS OF IRRADIATED ANIMALS
THE MECHANISM OF THE FORMATION OF MICRONECROTIC FOCI IN THE BONE MARROW OF ANIMALS ACTED ON BY PENETRATING RADIATION INVESTIGATED BY FLUORESCENCE AND ULTRA-VIOLET MICROSCOPY
Journal Article
·
Mon Dec 31 23:00:00 EST 1962
· Izvestiya Akademii Nauk SSSR, Seriya Biologicheskaya (U.S.S.R.)
·
OSTI ID:4718988
ON THE NATURE OF MICRONECROTIC FOCI IN HEMOPOIETIC ORGANS OF IRRADIATED ANIMALS
Journal Article
·
Thu Oct 31 23:00:00 EST 1963
· Izvestiya Akademii Nauk SSSR, Seriya Biologicheskaya (U.S.S.R.)
·
OSTI ID:4120911
THE MECHANISM OF THE FORMATION OF MICRONECROTIC FOCI IN THE BONE MARROW OF ANIMALS ACTED ON BY PENETRATING RADIATION INVESTIGATED BY FLUORESCENCE AND ULTRA-VIOLET MICROSCOPY
Journal Article
·
Wed Dec 31 23:00:00 EST 1958
· Biophysics (U.S.S.R.) (English Translation)
·
OSTI ID:4191220