THE INFLUENCE OF RADIUM ON THE OCULAR TISSUE OF THE RABBIT. V. ITS INFLUENCE ON THE LENS
In 9 cases of rabbits whose entire course was followed, cataract was observed which developed to total cataract during 3 years' observation. The destructive dose for the lens was approximately 200 mg hr in the infantile rabbit and approximately 500 mg hr in the full-grown rabbit. An opacity appeared initially on the lower part of the equator as a small vacuole. The developmental course was classified into 4 stages: appearance of a vacuole in the lower part of the equator; appearance and development of a vacuole and filamentous, punctate or cluster-like opacity in the cortex under the posterior capsule; appearance of opacity under the anterior capsule; and appearance of total cataract. Histologically, no characteristic findings were observed, but disturbance of the nuclear whorl, appearance of vacuoles under the anterior and posterior capsule and in the cortex, fragmentation and destruction of the fibers, accumulation of exudate, appearance of Morgagni's globules, and hypertrophy of the capsule were observed. The initial findings in the cataract seemed to be due to disturbances in the lens due to the direct effect ot radiation. (Abstr. Japan Med., 2: No. 6, June 1962)
- Research Organization:
- Kyoto Hospital
- NSA Number:
- NSA-16-025187
- OSTI ID:
- 4818929
- Journal Information:
- Acta Soc. Ophthalmol. Japan, Journal Name: Acta Soc. Ophthalmol. Japan Vol. Vol: 63
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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