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Spontaneous and X-ray-induced Somatic-chromosome Aberrations in the Chinese Hamster

Journal Article · · International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
The spontaneous and induced chromosome-aberration rates in the bone- marrow of the Chinese hamster, Cricetulus griseus, have been investigated. The spontaneous aberration rate is so low that no aberrations have yet been seen in control material. Two hours after irradiation the induced aberration rate was 0.0051 breaks per cell per r. The aberration rate fell rapidly with time after irradiation. Aberrations of all the expected types were found, but twohit aberrations did not appear until the sixth hour. The results support the conclusion that epithelioid cells in vitro have about the same sensitivity as a rapidly-dividing tissue in vivo, while fibroblasts are much more sensitive.
Research Organization:
Oak Ridge National Lab., Tenn.
Sponsoring Organization:
USDOE
NSA Number:
NSA-16-012911
OSTI ID:
4803512
Journal Information:
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, Journal Name: International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine Journal Issue: 2 Vol. 4; ISSN 0020-7616
Country of Publication:
Country unknown/Code not available
Language:
English

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