EFFECT OF SEGMENTAL INTESTINE SHIELDING ON MORTALITY FROM INTESTINAL RADIATION
Journal Article
·
· A.M.A. Arch. Pathol.
OSTI ID:4796710
Experiments were made to determine whether the absorptive function of the ileum is responsible for the protective effect of ileum shielding against acute intestinal radiation syndrome. A segment of the ileum was surgically isolated in some rats, the vascular supply being left intact and the continunity of the intestine being re-established by anastamosis of the transected ends. Irradiation experiments on operated and unoperated rats showed that shielding of a segment of ileum in continuity with the rest of the small intestine protected against radiation of the abdomen with 1,000 r, while shielding of a segment of isolated ileum did not. It is concluded that the protective effect of segmental intestine shielding is the reabsorption of fluids and electrolytes through the intact mucosa of the shielded part and that the intestinal radiation syndrome may be treated by restoration of fluid and electrolyte balance. (D.L.C.)
- Research Organization:
- Western Reserve Univ., Cleveland
- NSA Number:
- NSA-16-026748
- OSTI ID:
- 4796710
- Journal Information:
- A.M.A. Arch. Pathol., Journal Name: A.M.A. Arch. Pathol. Vol. Vol: 70
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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