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THE EXCRETION OF DESOXYCYTIDINE WITH THE URINE IN ACUTE RADIATION SICKNESS (in Russian)

Journal Article · · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR
OSTI ID:4792291

In experiments staged on irradiated rats (400, 700, and 800 r), a distinct rise of desoxycytidine excretion with the urine was revealed during the first day in all the animals. On the 3rd day this increase was changed by a normal content of the substance in the urine. Upon protection of the animals with cystamine in the majority of them there was no augmented discharge of desoxycytidine. The irradiation of dogs in a dose of 500 r was attended in the majority of cases by an elevated content of Diche-positive substances in the urine collected within the first 24 hours, The intensity of cysteine reaction in the urine of healthy persons and patients affected with different internal diseases ranges widely. In single irradiation of oncological patients (therapeutic x-ray dose) no augmented discharge of desoxycytidine with the urine could be revealed. (auth)

Research Organization:
Originating Research Org. not identified
NSA Number:
NSA-16-016293
OSTI ID:
4792291
Journal Information:
Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 7: No. 3; ISSN MERAA
Country of Publication:
Country unknown/Code not available
Language:
Russian

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