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EFFECTS OF X IRRADIATION ON ENZYME SYNTHESIS DURING LIVER REGENERATION

Journal Article · · Can. J. Biochem. and Physiol.
DOI:https://doi.org/10.1139/o62-072· OSTI ID:4789588
Twenty-four different enzymes or enzyme systems were assayed in regenerating rat liver from control and irradiated animals at various times after partial hepatectomy. X irradiation, either of the whole liver region or of an exteriorized liver lobule, interfered with the accumulation of only three of these enzymes: deoxycytidylate deaminase, thymidine phosphorylase, and NAD pyrophosphorylase. Irradiation did not affect the synthesis of related enzymes such as adenosine and guanine deaminases, and inosine and uridine phosphorylases. The effects of irradiation on enzyme synthesis in regenerating liver would appear to be highly selective. (auth)
Research Organization:
Atomic Energy of Canada Ltd., Chalk River, Ont.
NSA Number:
NSA-16-017464
OSTI ID:
4789588
Report Number(s):
AECL-1482
Journal Information:
Can. J. Biochem. and Physiol., Journal Name: Can. J. Biochem. and Physiol. Vol. Vol: 40
Country of Publication:
Canada
Language:
English

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