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The Origin of Taurine Excreted in the Urine after Whole-body Irradiation

Journal Article · · International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine

Irradiated rats excrete an excess of taurine in the urine during the first day after exposure. The injection of a large dose of cortisone has a similar effect. If rats are given smaller injections of cortisone daily for a week, subsequent irradiation no longer increases the excretion of taurine. Since both cortisone and ionizing radiation readily destroy lymphocytes, it is thought that the radiation-induced excretion of taurine may be wholly accounted for by damage to lymphoid tissues, which contain a high concentration of taurine. The amount of taurine excreted after irradiation may provide an estimate of the total amount of lymphoid tissue in the body.

Research Organization:
Australian Atomic Energy Commission Research Establishment, Sutherland, New South Wales
Sponsoring Organization:
USDOE
NSA Number:
NSA-17-000060
OSTI ID:
4784757
Journal Information:
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, Journal Name: International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine Journal Issue: 1 Vol. 5; ISSN 0020-7616
Country of Publication:
Country unknown/Code not available
Language:
English

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