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CONVERSION OF S$sup 35$-L-CYSTEIN TO TAURINE AND SULFATE IN THE NORMAL AND IRRADIATED RAT

Journal Article · · Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn.
OSTI ID:4809883
S/sup 35/-l-cysteine was injected into irradiated and control rats, and the excretion of taurine and sulfate followed for 3 days. The excess taurine excreted in the irradiated animals during the first 24 hrs following radiation had about the same specific activity as that of the controls, but during the following 2 days the taurine from the irradiated animals had a higher specific activity. The total amounts of sulfate excreted were the same in both the irradiated and control groups, but the specific activity of the sulfate from the control group was higher on the second and third days. When S/sup 35/-taurine was injected into irradiated and control rats, the taurine excreted had about the same specific activity in both groups. The results may be explained by an initial release of preformed taurine from muscle tissue, and a secondary release of cysteine from tissue proteins in the irradiated animals. (auth)
Research Organization:
Medical Nobel Inst., Stockholm; and Research Inst. of National Defense, Sundbyberg, Sweden
NSA Number:
NSA-16-026746
OSTI ID:
4809883
Journal Information:
Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn., Journal Name: Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn. Vol. Vol: 58; ISSN ACRAA
Country of Publication:
Country unknown/Code not available
Language:
English

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