BENEFICIAL EFFECT OF THE SHIELDING OF NONHOMOPOIETIC ORGANS ON THE RESTORATION OF HEMATOPOIESIS IN IRRADIATED MICE (in Russian)
In a given dose range, the outcome of radiation sickness depends mostly on the status of the blood circulatory system. This can be improved by introducing intact hematopoietic cells into irradiated animals. It was considered of interest to study the effect of other organs; thus the influence of unirradiated intestines on the hematopoiesis disturbed by exposure to radiation was investigated. The intestines of the mice were shielded by a lead foil, exposing the animals to 700 r of x rays. The results indicated that shielding of the intestines contributes considerably to regeneration of the bone marrow and the spleen. Restoration of the blood circulatory system damaged by radiation is not due to the migration and metaplasia of the shielded lymphatic elements but to the presence of humoral factors in the mucous membrane of the intestines which are able to reactivate the hematopoiesis. (TTT)
- Research Organization:
- Severtsov Inst. of Animal Morpholgy, Moscow
- NSA Number:
- NSA-16-030308
- OSTI ID:
- 4770425
- Journal Information:
- Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 2; ISSN RADOA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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