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FEATURES PECULIAR TO THE MECHANISM OF LEUKOPENIA IN ACUTE RADIATION SHOCK (in Russian)

Journal Article · · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR
OSTI ID:4767348

Experiments were carried out on 18 rabbits exposed to of leukopenia during acute radiation injuries. Simultaneous drops in hemoglobin, erythrocytes, and leukocytes were observed in all animals. The maximum drop in hemoglobin after exposure to 1000 r was about 3%, and 5% after 1500 and 2000 r exposures. The drop in erythrocytes in animals exposed to 1000 r was 2% and 11.8 and 13.1% at 1500 and 2000 r. A different picture was observed in the leukocyte reactions. After 2 to 3 hour exposure to 1000 r the leukocyte number dropped 69.9%. The number of leukocytes increased on the 3rd to 5th day, however, it never reached the initial level. Following a 2-hr exposure to 1500 r the number of leukocytes dropped 79.9%; rehabilitation began 5 hr later. The data indicate that smaller doses permit faster specific weight redistribution in leukopenic development, while with larger doses leukocytic redistribution is quickly replaced by heavy organic changes in the blood and marrow. (R.V.J.)

Research Organization:
Originating Research Org. not identified
NSA Number:
NSA-17-005853
OSTI ID:
4767348
Journal Information:
Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 7: No. 11; ISSN MERAA
Country of Publication:
Country unknown/Code not available
Language:
Russian

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