Studies on the Ralation between Dental Growth and Thyroid Gland Hazard by ¹³¹I

Journal Article · Sun Dec 31 23:00:00 EST 1961 · Radioisotopes (Tokyo)

DOI:https://doi.org/10.3769/radioisotopes.11.86· OSTI ID:4764232

HIGASHI, Tomomitsu; YAMAGUCHI, Toshimi; SUGA, Shoichi; NAKASHIMA, Mitsuru

The relation between dental growth and thyroid injuries from internal irradiation was studied in fetal and young rats from mothers injected with I¹³¹ while pregnant. About 0.3% of I¹³¹, injected in 250 mu c doses during the last period of pregnancy, passed through the placenta to fetuses within 24 hr following injection. Growth retardation was noted in the offspring of rats injected with 1 mu c of I¹³¹ during pregnancy. Dental impediments were noted in young rats from mothers injected with 1 mu c of I¹³¹. Histologic changes in dentation were not seen. Paper chromatograms of fetal thyroid tissue revealed monoiodotyrosine, diiodotyrosine, thyroxine, and unknown I¹³¹-labeled compounds. (C.H.)

• Research Organization: Nippon Dental Coll. Japan
• Sponsoring Organization: USDOE
• NSA Number: NSA-16-031461
• OSTI ID: 4764232
• Journal Information: Radioisotopes (Tokyo), Journal Name: Radioisotopes (Tokyo) Journal Issue: 1 Vol. 11; ISSN 0033-8303
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
BONES
CHROMATOGRAPHY
FETUSES
HORMONES
IODINE 131
PREGNANCY
RADIATION DOSES
RADIATION INJURIES
RATS
TEETH
THYROID