THE TRANSLOCATION OF THORIUM DAUGHTERS TO THE SKELETON OF THOROTRAST PATIENTS
Technical Report
·
OSTI ID:4751636
The thorium dioxide from Thorotrast injections is largely confied to the 1iver and spleen where most of the lesions also occur. Owing, however, to the translocation of the Th/sup 232/ daughters, radioactivity is spread to the skeleton and other tissues. The radiation dose from the skeletal deposit depends on the amount of Thorotrast injected and may be several orders of magnitude higher than that normally obtained from natural internal emitters. Thorotrast patients represent an unusual, irreplaceable opportunity to study the effects of chronlc radiation on man. Measurements were made of the Th/sup 232/, Ra/sup 228/ and Th/sup 228/ content of bone of patients. Extrapolating to the whole skeleton and correcting for the state of radioactive equilibrium in the liver and spleen, a good correlation is obtained between measurement and theory. From measurements to date, the Ra/sup 228/ content is in accord with known retention of Ra/sup 226/ in humans. No excess of Th/sup 228/ was found in bone to justify the previous assumption that wash out Th/sup 228/ is translocated from the R.E.S. to bone mineral. (auth)
- Research Organization:
- Argonne National Lab., Ill.
- DOE Contract Number:
- W-31109-ENG-38
- NSA Number:
- NSA-17-005707
- OSTI ID:
- 4751636
- Report Number(s):
- TID-15308; UAC-6011
- Country of Publication:
- United States
- Language:
- English
Similar Records
THE TRANSLOCATION OF Ra DAUGHTERS TO THE SKELETON OF THOROTRAST PATIENTS
Fracture occurrence from radionuclides in the skeleton
Bone tumors in Thorotrast patients. [Ra]
Technical Report
·
Tue Aug 14 00:00:00 EDT 1962
·
OSTI ID:4780197
Fracture occurrence from radionuclides in the skeleton
Journal Article
·
Thu Jun 01 00:00:00 EDT 2000
· Health Physics
·
OSTI ID:20075794
Bone tumors in Thorotrast patients. [Ra]
Journal Article
·
Wed Jan 31 23:00:00 EST 1979
· Environ. Res.; (United States)
·
OSTI ID:5457182