THE SYNTHESIS OF FATTY ACIDS BY RAT LIVER SLICES IN TRITIATED WATER
Journal Article
·
· Journal of Biological Chemistry (U.S.)
OSTI ID:4748500
Long chain fatty acids from rat liver slices were isolated after incubation in a medium enriched with tritiated water. The saturated fatty acids were separated by lead salt precipitation and the incorporation of radioactivity into the individual acids determined. The major portion of radioactivity was found in palmitic and stearic acids. Sequential degradation of the saturated fatty acids was carried out and the intramolecular location of tritium determined. Contrary to expectation, more tritium was found in the odd-numbered carbon atoms than the even-numbered. It is suggested that an exchange reaction between reduced triphosphopyridine nucleotide and water occurs before or during fatty acid synthesis, and that the exchange is essentially complete. (auth)
- Research Organization:
- National Inst. of Arthritis and Metabolic Diseases, Bethesda, Md.
- NSA Number:
- NSA-17-015595
- OSTI ID:
- 4748500
- Journal Information:
- Journal of Biological Chemistry (U.S.), Journal Name: Journal of Biological Chemistry (U.S.) Vol. Vol: 238; ISSN JBCHA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
In vivo incorporation of labeled fatty acids in rat liver lipids after oral administration
Labeling Fatty Acids by Exposure to Tritium Gas. III. Methyl Stearolate and Methyl Linolenate
Control of bovine hepatic fatty acid oxidation
Journal Article
·
Sat Aug 01 00:00:00 EDT 1987
· Lipids; (United States)
·
OSTI ID:5726261
Labeling Fatty Acids by Exposure to Tritium Gas. III. Methyl Stearolate and Methyl Linolenate
Journal Article
·
Sun Jul 01 00:00:00 EDT 1962
· Journal of Organic Chemistry
·
OSTI ID:4675778
Control of bovine hepatic fatty acid oxidation
Journal Article
·
Mon Sep 01 00:00:00 EDT 1986
· J. Dairy Sci.; (United States)
·
OSTI ID:6703443