CONTAMINATION OF MILK BY RADIOIODINE

Journal Article · Sat Nov 11 04:00:00 EST 1961 · Lancet (England)

DOI:https://doi.org/10.1016/S0140-6736(61)92578-8· OSTI ID:4748471

Johnson, A; Pochin, E E

To show the speed and completeness with which oral iodides in pharmacological dosage inhibit further radioiodine uptake, the length of time during which thyroid iodine uptake continues to be depressed following such a dose was studied. Thyroid uptakes were measured by profile countlng methods at 3 hr after an oral test dose of I/sup 132/, before a 200-mg oral dose of stable iodide, and at various intervals after it. Preliminary data on 3 subjects are consistent in showing that the uptake is small at 1 day after iodide, is still only about 20% of normal at 2 days, but has returned to about 50% of normal at 3 to 4 days after the dose. It would seem, therefore, that doses every few days, rather than a single dose, would be required to suppress thyroid uptake of radioiodine during any prolonged period of high milk contamination with I/sup 131/ . There is some evidence suggesting a faster iodine turnover in children than adults; this indicates a need for more frequent and perhap daily doses if I/sup 131/ uptake is to be kept at a low value. (P.C.H.)

• Research Organization: University Coll. Hospital Medical School, London
• NSA Number: NSA-17-015605
• OSTI ID: 4748471
• Journal Information: Lancet (England), Journal Name: Lancet (England) Vol. Vol: 2; ISSN LANCA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
CONTAMINATION
COUNTERS
INTESTINE
IODIDES
IODINE 131
IODINE 132
MAN
MEASURED VALUES
METABOLISM
MILK
QUANTITY RATIO
THYROID
VARIATIONS