THE RATE OF RETURN OF RADIOIODINE UPTAKE BY THE NORMAL THYROID AFTER SUPPRESSION BY PHARMACOLOGICAL DOSES OF STABLE IODIDE

Journal Article · Wed May 01 04:00:00 EDT 1963 · Health Physics (England)

DOI:https://doi.org/10.1097/00004032-196305000-00009· OSTI ID:4705601

Johnson, A E

It is well known that large doses of stable iodine in any form from Lugol's iodine to Telepaque'' will inhibit thyroid uptake of radioiodine for a variable period, which may be several months in the case of a cholecystogram. It has also been shown that further uptake by the thyroid of radioiodine can be suppressed by pharmacological doses of stable iodide given up to 4 hr after single orai doses of radioiodine. A study was undertaken to determine the duration of the inhibition following a pharmacoiogical dose. Observations after a single oral 200-mg dose of stable iodide show that uptake returns to >50% of the normal value by 3 days, to >80% by 4 days, and to about the normal level by 8 days after the dose. (auth)

• Research Organization: Univ. of London
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-024859
• OSTI ID: 4705601
• Journal Information: Health Physics (England), Journal Name: Health Physics (England) Vol. Vol: 9; ISSN HLTPA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
IODIDES
IODINE
IODINE ISOTOPES
MAN
METABOLISM
QUANTITY RATIO
THYROID