EXPERIMENTAL RESULTS FROM THE COMBINED ADMINISTRATION OF DEHYDROASCORBIC ACID AND IONIZING RADIATION ON YOSHIDA SARCOMA IN RATS
Attempts were made to determine whether dehydroascorbic acid (DHAA) and radiation have additive effects by in vivo experiments with Yoshida sarcoma in rats. The rats were injected with 45000 tumor cells subcutaneously, and 7 days later were injected with 2 mg/kg DHAA intraperitoneally. Some animals were x irradiated on the 8th, 10th, and 13th days after tumor implantation with 300-r daily doses. An additive effect of DHAA and x rays on the inhibition of tumor growth was demonstrable. The average tumor weight on the 16th day after implantation in the 4 groups of rats (control, injected, irradiated, injectedirradiated animals) was as follows: 15.56, 14.00, 9.91, and 7.23 g, respectively. (TCO)
- Research Organization:
- Universitat, Vienna
- NSA Number:
- NSA-17-017905
- OSTI ID:
- 4737425
- Journal Information:
- Zeitschrift fuer Krebsforschung (West Germany) Superseded by Z. Krefsforsch. Klin. Onkol., Journal Name: Zeitschrift fuer Krebsforschung (West Germany) Superseded by Z. Krefsforsch. Klin. Onkol. Vol. Vol: 64; ISSN ZEKBA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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