CESIUM$sup 137$ METABOLISM IN MAN

Technical Report · Mon Jan 01 04:00:00 EST 1962

OSTI ID:4709207

Rosoff, B; Cohn, S H; Spencer, H

The main pathway of Cs/sup 137/ excretion in man following either intravenous or oral administration is via the kidney. The urinary to fecal ratio is approximately 10 : 1. Orally administered Cs/137/ is rapidly and almost completely absorbed. The metabolism of the radioisotope was shown to be similar following either intravenous or oral administration. Cs/sup 137/ disappears very rapidly from plasma and is taken up by red blood cells. The biological half-life of cesium in man deterrained by analyses of excreta of two patients was found to be 50 and 60 days respectively. These values are similar to the biological half- lives obtained by long term whole-body counting studies. The distribution of Cs/ sup 137/ in man is fairly uniform in the soft tissues and the concentration decreases with time at different rates. Attempts to enhance the excretion rate of Cs/sup 137/ with diuretics, corticosteroids, and ion exchange resins were unsuccessful. (auth)

• Research Organization: New York Univ., New York; Goldwater Memorial Hospital, New York; Veterans Administration Hospital, Hines, Ill.; Brookhaven National Lab., Upton, N.Y.; and Montefiore Hospital, New York
• NSA Number: NSA-17-012100
• OSTI ID: 4709207
• Report Number(s): TID-17541
• Country of Publication: United States
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD PLASMA
CESIUM 137
CURRENTS
DISTRIBUTION
DRUGS
ELECTRIC ARCS
ELECTRIC DISCHARGES
ERYTHROCYTES
GASES
HALF-LIFE
HORMONES
ION EXCHANGE MATERIALS
IONIZATION
KIDNEYS
LOSSES
MAN
MEASURED VALUES
METABOLISM
NUMERICALS
QUANTITY RATIO
RESINS
STEROIDS
TEMPERATURE
THERMAL CONDUCTIVITY
TISSUES
URINE