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THE EMPLOYMENT OF SEROTONIN IN THE PROPHYLAXIS OF ACUTE RADIATION SICKNESS IN MONKEYS (in Russian)

Journal Article · · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR
OSTI ID:4700655
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5-hydroxytryptamine hydrochloride was used intramuscularly for the prevention of radiatlon sickness in 48 macaque monkeys in doses ranging from 35 to 175 mg/kg. Serotonin produced a marked protective effect with a dose of 35 to 40 mg/kg in total gamma irradiation (630 r: LD90%). The protective action was manifested by alleviation of symptoms of radiation sickness and survival of 35% of the animals in comparison with irradiated control animals. (P.C.H.)
Research Organization:
Inst. of Experimental Pathology and Therapy, Academy of Sciences, USSR; and Inst. of Experimental and Clinical Oncology, Moscow
NSA Number:
NSA-17-025053
OSTI ID:
4700655
Journal Information:
Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 8: No. 4; ISSN MERAA
Country of Publication:
Country unknown/Code not available
Language:
Russian

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Related Subjects

AMINES
BIOLOGY AND MEDICINE
GAMMA RADIATION
MONKEYS
RADIATION DOSES
RADIATION PROTECTION
RADIATION SICKNESS
SEROTONIN
SURVIVAL TIME