CERTAIN PROBLEMS OF THE CLINICAL PICTURE AND COURSE OF ACUTE RADIATION SICKNESS IN MONKEYS

Journal Article · Tue Sep 01 00:00:00 EDT 1959 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4239053

Bagdasarov, A A; Raushenbach, M O; Sukyasyan, G V; Abdullaev, G M; Novikova, M N; Lagutina, N Ya; Samoilina, N L; Chernov, G A

The authors studied the course of acute radiation sickness in 8 monkeys (Macacarhesus) subjected to single whole-body x irradiation (in the dose of 540 r). Four monkeys underwent treatment with polyvinylpyrollidon, colloid infusin, thrombocytic mass, hemostimulants, and other pharmacological substances. Four monkeys served as control. All monkeys developed acute radiation sickness with manifestations of toxemia and characteristic changes in the peripheral blood and bone marrow. There were observed regular changes in the coagulating system of the blood, as well as in the content of serotonin and properdin in the blood. The control monkeys perished in the course of the first two weeks following irradiation, while all the treated monkeys survived. At the 40th day following irradiation the indices of hemo- and myelogram in the monkeys treated reached the initial values. Clinically the monkeys were absolutely healthy. (tr-auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-14-001416
• OSTI ID: 4239053
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BACTERIA
BIOLOGY AND MEDICINE
BLOOD CELLS
BODY
BONE MARROW
COAGULATION
COLLOIDS
DRUGS
IMMUNITY
MONKEYS
ORGANIC NITROGEN COMPOUNDS
POLYVINYLS
PVP
PYRROLIDONES
RADIATION DOSES
RADIATION SICKNESS
X RADIATION