Experiments on the Radioprotective Action of Dimethyl Sulphoxide
Journal Article
·
· International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
The radioprotective action of dimethyl sulfoxide against a lethal dose of x rays was investigated in two strains of mice. The protection was somewhat better in CBA/Rij than in C57BL/Rij mice. At protective doses a marked fall in the oxygen tension in the spleen was found. This effect was greater in the CBA/ Rij than in the C57BL/Rij mice. The intraperitoneal injection of dimethyl sulfoxide caused an abrupt rise in blood pressure lasting only a few minutes. The mechanism of action of dimethyl sulfoxide in the mouse is discussed. (auth)
- Research Organization:
- National Defence Research Organization TNO, Rijswijk (Z.H.), Netherlands
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-17-019922
- OSTI ID:
- 4699666
- Journal Information:
- International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, Journal Name: International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine Journal Issue: 2 Vol. 6; ISSN 0020-7616
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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