LYMPHOCYTE PRODUCTION MEASURED BY EXTRACORPOREAL IRRADIATION, CANNULATION AND LABELING TECHNIQUES
Conference
·
OSTI ID:4695369
The labeling of newly-formed lymph cells with tritiated thymidine, lymphatic duct cannulation, and the peripheral destruction of lymphocytes by extracorporeal irradiation of the blood were used to estimate the mass of prestored lymphocytes and the relative degree of recirculation of 1ymphocytes from blood to lymph and back again. Topics discussed include the effects of extiacorporeal irradiation on the histologic picture of the lymphoreticular tissue, the influence of extracorporeal irradiation upon the thoracic duct output, and preliminary observations on labeling of lymphocytes by tritiated thymidine at the completion of extracorporeal irradiation. Data indicate that the mass of preformed small lymphocytes may be as large as 40 times that present in peripheral blood, that the blood feeds lymphocytes primarily into the lymph, and presents strong evidence for lymphocyte recycling. (C.H.)
- Research Organization:
- Brookhaven National Lab., Upton, N.Y.
- DOE Contract Number:
- AT(30-2)-GEN-16
- NSA Number:
- NSA-17-031852
- OSTI ID:
- 4695369
- Report Number(s):
- BNL-7137; CONF-100-1
- Country of Publication:
- United States
- Language:
- English
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