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Radiochromium-Labeled Lymphocytes in the Rat.

Journal Article · · Experimental Biology and Medicine

A technic is described for labeling rat lymphocytes, collected from intestinal lymph, with radiochromium without impairing their motility. After intravenous administration, these labeled cells disappeared rapidly from the circulating blood, reappeared to a limited extent within 6 hours, then continued to disappear at a very slow rate (about 1.1% per hour). When the rat's intestinal lymphatic trunk was cannulated, 4 to 7% of the labeled lymphocytes appeared in the lymph within 4 days, with maximal lymphatic radioactivity occurring between the 24th and 38th hours.

Research Organization:
Mayo Clinic, Rochester, MN (United States)
Sponsoring Organization:
USDOE
NSA Number:
NSA-17-031917
OSTI ID:
4682941
Journal Information:
Experimental Biology and Medicine, Journal Name: Experimental Biology and Medicine Journal Issue: 2 Vol. 113; ISSN 1535-3702
Country of Publication:
Country unknown/Code not available
Language:
English