RADIATION SEQUELAE IN THE BLADDER AND URINARY TRACT IN WOMEN WITH CERVICAL CANCER AND ITS TREATMENT
Radioinduced injuries of the urinary tract are considered in relation to changes occurring in the bladder, ureters, and kidneys. Changes that may be observed in the bladder are: hemorrhagic cystitis with or without hematuria, bullous edema, ulceration, teleangiectasia, vesicovaginal fistula, contracted bladder, and other late occurrences such as sclerosis and incontinence. The initial inflammatory changes in bladder mucosa may be reversible but the late fibrosis is not. Conservative treatment of bladder injury consists of the use of spasmolytics, heat applications, and instillation of antibiotics into the bladder along with corticosteroids and vitamin A. Surgical intervention may be necessary to correct a fibrotic shrunken bladder or vesicovaginal fistula. The most severe complication of radiotherapy may be injury to the ureters, which may account for 10% of the fatalities resulting from cervical carcinoma. Cortisone may be used for conservative treatment, whereas surgery may be necessary to form a ureteral- intestinal the damaged segment. Use of plastic materials to replace the segment is described and success with various surgical technics is discussed. Primary radioinjury of the kidney is a relatively rare sequel to treatment of cervical cancer, and secondary damage from hydronephrosis and ascending pyelonephritis is much more frequent. Complications and their treatment in 103 cases are described. (H.H.D.)
- Research Organization:
- Chirurgische Universitaetsklinik, Tuebingen, Ger.
- NSA Number:
- NSA-17-023115
- OSTI ID:
- 4692227
- Journal Information:
- Fortschritte der Medizin (West Germany), Journal Name: Fortschritte der Medizin (West Germany) Vol. Vol: 79; ISSN FMDZA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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