PROTECTIVE EFFECTS OF ETHYLPALMITATE ON X-IRRADIATED MICE (in German)
Journal Article
·
· Strahlentherapie (West Germany)
OSTI ID:4686243
An ethyl ester of palmitic acid (ethylpalmitate) increased the survival rate of x irradiated mice, if it was injected intravenously in small doses 24 to 72 hours before irradiation. This protective effect could be shown also by measuring the effect on body weight after irradiation. The radiation protective effect of the ethylpalmitate was obtained at 25 to 100 mg/animal; it was dose dependent and increased with increasing dose. The toxicity of ethylpalmitate was tested using non-irradiated mice. The mortality increased from about 5% to 85% in the dose range of 25 to 100 mg/animal; female animals were more sensitive than male ones. Purest ethylpalmitate was more toxic than ethylpalmitate of less purity. The problem is discussed whether chemical splenectomy caused by the ethylpalmitate is responsible for the radiation protection effect of this substance. (auth)
- Research Organization:
- Universitat, Freiburg i. B.; Heiligenberg-Instituts, Heiligenberg Baden, Ger.
- NSA Number:
- NSA-17-028764
- OSTI ID:
- 4686243
- Journal Information:
- Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 121; ISSN STRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- German
Similar Records
PROTECTIVE ACTION OF ETHYL PALMITATE AGAINST ROENTGEN RADIATION
Radiation Protective Effect of Ethyl Palmitate
Protection of mice against fission neutron irradiation by WR-2721 or WR-151327
Journal Article
·
Mon Dec 31 23:00:00 EST 1962
· Arch. Exptl. Pathol. Pharmakol.
·
OSTI ID:4659079
Radiation Protective Effect of Ethyl Palmitate
Journal Article
·
Sun Dec 31 23:00:00 EST 1961
· Naturwissenschaften (West Germany)
·
OSTI ID:4839359
Protection of mice against fission neutron irradiation by WR-2721 or WR-151327
Journal Article
·
Sat Feb 28 23:00:00 EST 1987
· Radiat. Res.; (United States)
·
OSTI ID:6515616