THE RECOVERY OF HEMATOPOIESIS IN DOGS SURVIVING THE ACUTE RADIATION SYNDROME (in Russian)
Dogs were given a Co/sup 60/ r dose of 400 r (LD/sub 50/30/) and 650 r (LD/sub 80/30/). After irradiation with a 650 r dose, part of the dogs were treated with antibiotics, vitamins and blood transfusions. This treatment increased the survivial by 60%. The leukocytes, neutrophils, lymphocytes, erythrocytes, thrombocytes, and hemoglobin content were determined for periods of up to 3 years after the irradiation. With a 400 r dose, the neutrophil count attained 90% of its initial values between 6 and 10 months after the irradiation, but the lymphocyte count was a factor of two less than it was before the irradiation. The ratio of myeloid cells to erythroid cells was lower in the bone marrow of the irradiated animals than in the controls 3 years after the irradiation, although the number of neutrophils and erythrocytes in the peripheral blood was found to be normal. About a year is required to establish normal granulopoiesis and thrombopoiesis in the irradiated dogs, but normal lymphopoiesis was not observed in a single animal even three years after the irradiation. Normal leucopoiesis was established more rapidly in dogs given therapeutic treatment than in the untreated dogs. (TTT)
- Research Organization:
- Kirov Academy of War Medicine, Leningrad
- NSA Number:
- NSA-17-030421
- OSTI ID:
- 4686206
- Journal Information:
- Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 3; ISSN RADOA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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Related Subjects
ATOMIC MODELS
BIOLOGY AND MEDICINE
BLOOD
BLOOD CELLS
BLOOD FORMATION
BONE MARROW
CALCIUM FLUORIDES
COBALT 60
CRYSTALS
DIPOLES
DOGS
EFFICIENCY
EMISSION
ERYTHROCYTES
HEMOGLOBIN
IONS
LEUCOCYTES
LYMPHOCYTES
MAGNETIC FIELDS
MEASURED VALUES
MEDICINE
NEUTROPHILS
NUMERICALS
PLATELETS
QUANTITY RATIO
RADIATION DOSES
RADIATION SICKNESS
RADIOSENSITIVITY
SPECTRA
SURVIVAL TIME
THALLIUM
TRANSFUSIONS
TRANSIENTS
TRANSPLANTS
VARIATIONS
VITAMINS
ZEEMAN EFFECT