RESTORATION OF HEMATOPOIESIS IN RABBITS IN VARYING SEVERITY OF ACUTE RADIATION SICKNESS (in Russian)
The restoration of hematopoiesis was studied in 150 rabbits. The animals were subjected to x irradiation in doses of 200, 600, 800, and 1,800 r. The centers of hematopoiesis and peripheral blood were investigated before the irradiation and on the 1st, 3rd, 5th, 7th, 10th, 12th, 15th, 2Oth, 3Oth, 4Oth, and 5Oth day following it. The data obtained testify to the fact that in severe, moderate, and mild lesions the restoration takes place simultaneously in the white and red marrow, with a certain prevalence in the first days of the somewhat atypical regeneration of granulopoiesis. Subsequently the bone marrow produces predominantly erythroblasts, then the granulopoiesis activation begins at a later date following irradiation, on the 15th to 2Oth day. Elements of regeneration could be observed in rabbits even in absolutely lethal lesions. The appearance and markedness of regeneration of thrombopoiesis and lymphopoiesis is also closely connected with the severity of affection. The restoration of thrombopoiesis coincides with manifestations of regeneration in the erythrocytic series of the bone marrow. (auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-15-019190
- OSTI ID:
- 4007401
- Journal Information:
- Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 6: No. 2; ISSN MERAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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