EFFECTS OF X-IRRADIATION ON PROTEOLYTIC ENZYMES OF MOUSE SPLEEN
Journal Article
·
· Ann. Rept. Radiation Center Osaka Prefect.
OSTI ID:4684864
Changes in proteolytic activity concerned with an increase in protein- free DNA in the x-irradiated mouse spleen were investigated. After 1000 r x irradiation, the proteolytic activity of spleen increased linearly up to 1.9 times the controls during 4 hr, and the rate of protein-free DNA also increased over 2 times during 6 hr. The relation between the changes is discussed. It was concluded that the change in protein-free DNA comes as a result of splitting from the DNA protein complex (insoluble in 0.14M NaCl) of which the protein moiety has been digested by the intracellular proteolytic enzymes being progressively activated by irradiation. (P.C.H.)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-17-033631
- OSTI ID:
- 4684864
- Journal Information:
- Ann. Rept. Radiation Center Osaka Prefect., Journal Name: Ann. Rept. Radiation Center Osaka Prefect. Vol. Vol: 3
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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