STUDIES OF THE LABILE PHASE OF THE RADIATION EFFECT USING THE RADIATION- INDUCED INHIBITION OF GLYCOLYSIS OF THE EHRLICH-ASCITES CARCINOMA
Thesis/Dissertation
·
OSTI ID:4665673
Radiation-induced inhibition of anaerobic glycolysis in tumor cells is increased when oxygen is present during irradiation. The influence of temperature was measured. Decreased temperature results in an enhanced inhibition. After irradiation with 30 kr, the quotient of glycolysis of cells irradiated in the presence of oxygen to those without oxygen is 1: 12. Treatment of anaerobic tumor cells with oxygen after irradiation results in an increase of glycolysis. This effect is explained by a labile phase of the radiation effect immediately after irradiation. The effects of oxygen on Ehrlich-ascites carcinoma of mice during and after irradiation are discussed. (Gmelin Inst.)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-17-031959
- OSTI ID:
- 4665673
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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