THE LABILE PHASE OF RADIATION EFFECTS

Journal Article · Sun May 01 04:00:00 EDT 1960 · Strahlentherapie (West Germany)

OSTI ID:4169371

Dittrich, W

S>to visible radiobiological effects by a more or less long chain of reactions. During an"unstable phase" of the radiation effect, whose duration depends very much on the conditions of the experiment, suitable external interventions influence-increasing or decreasing-the end effect. This is illustrated by two examples. The irradiated Ehrlich ascites carcinoma of the mouse was treated with oxygen following the irradiation which increased the induction of chromosome aberrations in mitosis cells in one case, and decreased it in the other case considerably. In the second example, in which the anaerobic glycolysis of tumor ascites cells of the Ehrlich carcinoma of the mouse was inhibited by x-rays, oxygen has at least 2 different points of action in its effect on the radiation reaction. The existence of an"unstable phase" of the radiation effect can also be accommodated in the hit theory by the assumption that the effect likelihood of a hit becomes fixed finally only during the reactions following the physical primary happening under the influence of the secondary conditions. (auth)

• Research Organization: Universitats-Frauenklinik Hamburg-Eppendorf, Ger.
• NSA Number: NSA-14-014711
• OSTI ID: 4169371
• Journal Information: Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 112; ISSN STRAA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

ANIMAL CELLS
BIOCHEMISTRY
BIOLOGY AND MEDICINE
CANCER
CHROMOSOMES
GLYCOLYSIS
MICE
MITOSIS
MUTATIONS
OXYGEN
RADIATION EFFECTS
RADIOBIOLOGY