ELECTROENCEPHALOGRAPHIC FINDINGS IN MAMMALS AFTER ROENTGEN IRRADIATION

Journal Article · Thu May 10 04:00:00 EDT 1962 · Aerztliche Forschung (West Germany) Discontinued

OSTI ID:4654985

Gangloff, H

Previous studies indicated that, with the exception of the cerebral cortex, the central nervous system shows litile change in electrical activity after exposure to ionizing radiation at doses below 2000 r. However, it was possible to show that in cats with stereotactically implanted electrodes, relatively small doses of x rays (200 and 400 r at 40 and 110 r/min) elicit changes in subcortical bioelectric activity. These doses produced only slight general symptoms of radiation sickness and no neurologic symptoms. Changes in the electroencephalogram are manifested by spike discharges appearing within an hour of exposure and disappearing after several days. Such changes could be elicited in welldefined regions such as the horn of Ammon in the hippocampus after wholebody or head irradiation. The spike discharges reached max intensity within 3 to 7 hr postexposure, and the hippocampus activity could be detected for as long as 10 to 14 days afterward. It was more intense when the animals were asleep and was attenuated by their awakening. Similar results were obtained in rabbits. (BBB)

• Research Organization: Universitat, Munich
• NSA Number: NSA-17-033627
• OSTI ID: 4654985
• Journal Information: Aerztliche Forschung (West Germany) Discontinued, Journal Name: Aerztliche Forschung (West Germany) Discontinued Vol. Vol: 16; ISSN ARZFA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

ANIMALS
BIOLOGY AND MEDICINE
BRAIN
CATS
ELECTRIC POTENTIAL
ELECTRODES
ELECTROENCEPHALOGRAPHY
NERVOUS SYSTEM
PHYSIOLOGY
RABBITS
RADIATION EFFECTS
RADIATION SICKNESS
RECORDING SYSTEMS
SLEEP
VARIATIONS
X RADIATION