Fragmentation of biomolecules using slow highly charged ions
- Lawrence Livermore National Lab., CA (United States)
- Missouri Univ., Rolla, MO (United States). Dept. of Physics
We present first results of biomolecular fragmentation studies with slow highly charged ions (HCI). A layer of the tripeptide RVA was deposited on gold targets and irradiated with slow (few 100 keV) ions, e.g. Xe{sup 50+} and Xe{sup 15+}, extracted from the LLNL EBIT (electron beam ion trap). The secondary ions released upon ion impact were mass analyzed via Time-Of-Flight Secondary-Ion-Mass-Spectrometry (TOF-SIMS). The results show a strong dependence of the positive and negative ion yields on the charge state of the incident ion. We also found that incident ions with high charge states cause the ejection of fragments with a wide mass range as well as the intact molecule (345 amu). The underlying mechanisms are not yet understood but electron depletion of the target due to the high incident charge is likely to cause a variety of fragmentation processes. 6 refs., 2 figs.
- Research Organization:
- Lawrence Livermore National Lab., CA (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- W-7405-ENG-48
- OSTI ID:
- 464547
- Report Number(s):
- UCRL-JC--125760; CONF-961110--33; ON: DE97051953
- Country of Publication:
- United States
- Language:
- English
Similar Records
Fragmentation of biomolecules using slow highly charged ions
Electronic sputtering and desorption effects in TOF-SIMS studies using slow highly charged ions like Au{sup 69+}
Super TOF secondary ion mass spectroscopy using very highly charged primary ions up to Th{sup 70+}
Journal Article
·
Fri Jan 31 23:00:00 EST 1997
· AIP Conference Proceedings
·
OSTI ID:587075
Electronic sputtering and desorption effects in TOF-SIMS studies using slow highly charged ions like Au{sup 69+}
Conference
·
Sun Sep 01 00:00:00 EDT 1996
·
OSTI ID:397157
Super TOF secondary ion mass spectroscopy using very highly charged primary ions up to Th{sup 70+}
Conference
·
Sun Oct 01 00:00:00 EDT 1995
·
OSTI ID:201647